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Extrapleural pneumonectomy is a surgical treatments for malignant pleural mesothelioma. It is an invasive and complex operation, and performed only on patients with early stage localized disease that has not spread to the lymph nodes or invaded surrounding tissues and organs. 

For the suitable candidate, is potentially the most effective method for disease control of malignant mesothelioma. It can slow disease progression, improve quality of life, especially breathing. When combined with radiation and chemotherapy, extrapleural pneumonectomy can have a significant impact on life expectancy.

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